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The standard of care usually involves the prescription of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) like ibuprofen or stronger corticosteroids like prednisone

Fracture repair: general aspects and influence of osteoporosis and anti-osteoporosis treatment

Hasegawa J, Inoki K, Weisman LS

Brief Funct Genomics (2018) 17(4):2078

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Studies have shown that B cells also play a role in the progression of osteoarthritis (OA), as their proliferation and differentiation capabilities are altered in the synovium of OA patients ( Research indicates that B cells can secrete various pro-inflammatory factors, including interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-), which induce chondrocyte death and cartilage matrix destruction (126) ( Figure 4 )