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( B ) Immunoblot analysis to detect HJURP, KNL2, CENP-C, and SNAP-CENP-A with anti-HJURP, anti-KNL2, anti-CENP-C, and anti-HA antibodies, respectively, in AID-based CENP-C knockout cells with Tet-based HJURP-cKO background expressing EGFP-HJURP or EGFP-HJURP 2E in the presence (+) or absence () of IAA (3.5 h)

WHO has disclosed that over 50 million people globally suffer from dementias, including Alzheimers disease, and that it is expected to rise to over 152 million by the year 2050

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Managing these conditions often involves reducing inflammation and supporting immune regulation