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Food Chemistry,301, 125286

A meta-analysis study showed that for L-carnitine to have significant effects on FBG levels in patients with diabetes, 2 grams/day should be taken as a supplement for at least 36 weeks, also it is estimated that 2 g of L-carnitine per day is needed for at least 106 weeks to have a significant effect on HbA1c levels (87)

Amino acid modifications in the N-terminus and at certain positions in the C-terminus are involved in the resistance to DPP-4 inhibition, thus prolonging its half-life

doi: 10.1186/1471-2318-4-8 65 GholamnezhadZBoskabadyMHHosseiniMSankianMKhajavi RadA

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Guo GL, Chiang JYL