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Description

Phytochemicals in cancer treatment: From preclinical studies to clinical practice

Disulfiram metabolites, including diethyldithiocarbamate (DDC), carbon disulfide (CS2), S-methyl N,N-diethylthiocarbamate sulfoxide (DETC-sulfoxide), S-methyl N,N-diethylthiocarbamate sulfone (DETC-sulfone), diethylthiomethylcarbamate, S-methyl-DDC, methyl diethylthiocarbamate sulfoxide, and methyl diethylthiocarbamate sulfone, play a crucial role in its pharmacological effects (PharmGKB, 2023)

F.SoaresV

Nov 2013;29(6):673-9

December 28, 2015

Under normal conditions, the antioxidant defence systems are probably capable of maintaining a low steady-state level of damage and thus protecting the cells (Zhou et al.2003)