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The main drawback is the dosage, which requires taking a few capsules

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In a preclinical model of RA, ITA reduced arthritis severity and bone erosion by suppressing the proliferation and migration of FLSs

Apocynin is a bioactive phenol extracted from the roots of Apocynum venetum L., and as a NOX2 inhibitor, it can prevent ROS production and reduce inflammatory responses (Philippens et al., 2013)