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J Pharm Biomed Anal

doi:10.1136/annrheumdis-2015-208840 123Drugs and Lactation Database (LactMed)

After reconstitution: Store at 28 C , protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling

A cross-sectional study of patients with periorbital pigmentation found a significant association between dark circles and low B12 levels, noting that B12 supplementation could serve as an adjunctive treatment in affected patients