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Transgenerational effects on the gene transcriptome of chicken liver

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The pathogenesis involves adipocyte dysfunction and systemic insulin resistance, which induce a lipotoxic milieu, mitochondrial dysfunction, and chronic inflammation through the systemic release of cytokines [14]

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The phenomena that high-fat diet impairs glucose homeostasis has been reported in rainbow trout 49,50

[DOI] [PubMed] [Google Scholar] 63