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Its frequency continues to rise, affecting approximately 1% of the general population and more than 5% of workers in specific industries that involve repetitive hand and wrist movements, with a female-to-male ratio of approximately 3:1

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J Endocrinol 219(3):183193 Wmeau J-L, Klein M, Sadoul J-L, Briet C, Vlayoudom-Cphise F-L (2018) Graves disease: introduction, epidemiology, endogenous and environmental pathogenic factors

Anti-viral cocktail therapy down-regulated the IL-6-STAT3-CXCL1/MCP-1 signaling pathway mediated by toll-like receptor 9 (TLR9), significantly reduced serum lipase and amylase, and decreased neutrophils and macrophages infiltration [90]

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