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This polymorphism is a naturally occurring human variant of BDNF that results in the amino acid substitution Val66Met in the prodomain of the bdnf gene [185, 186]

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Researchers frequently compare it to other metabolic peptides such as those described in our best peptides for weight loss research guide, where it is often positioned as a selective, non-GH-axis alternative with a narrow pharmacological footprint

doi:10.1038/s41598-019-40230-4