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Certain medications deplete folate levels

It is observed that in patients who are deficient in Vitamin B12, the CBC would show anemia, which manifests as a decrease in both hemoglobin and hematocrit

It also prevents lipogenesis, the synthesis of new fat reserves

5,10-Methylene tetrahydrofolate (THF) is required for the synthesis of nucleic acids and is reduced to 5-methyl THF by methylene THF reductase, a flavin-dependent enzyme that uses NADPH as a cofactor

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That's where B12 injections come in