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Data were collected from parents through a self-administered questionnaire and from study subjects through a face-to-face interview by trained data collectors

The upregulation of Sirt3 and Sirt5 may have anti-apoptotic activities (Kincaid and Bossy-Wetzel, 2013), but decreased expression of Sirt1 disrupts the Sirt1-PGC-1 inter-relationships (Lavu et al., 2008)

Biologically independent duplicate experiments were performed and imaged

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