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doi: 10.3389/fmicb.2026.1771755 Received 19 December 2025 Revised 11 February 2026 Accepted 17 February 2026 Published 16 March 2026 Volume 17 - 2026 Edited by Takema Fukatsu, National Institute of Advanced Industrial Science and Technology (AIST), Japan Reviewed by Vincent Joseph Starai, University of Georgia, United States Achmad Gazali, National Agriculture and Food Research Organization, Japan Updates Copyright 2026 Yousef, Masters, Wu, Hong, ONeill, Turner, Ward and Taylor

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Conversely, exogenous GSH supplementation can alleviate IS by increasing striatal dopamine levels, which upregulate GSH synthase and homocysteine, thereby enhancing GSHs therapeutic efficacy in the brain (Wang H

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