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doi: 10.1016/j.cgh.2021.04.028 98 ZschbitzSChengT-YDNeuhouserMLZhengYRayRMMillerJWet al

an event characterized by loss of cell membrane asymmetry, cell shrinkage, and an increase in intracellular Ca 2+ , primarily due to dysregulated Ca 2+ influx [436]