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The central challenge for this fungal pretreatment, however, is economic: the process is often slower and less amenable to continuous industrial operation than established physicochemical methods (e.g., steam explosion, acid hydrolysis), raising concerns about capital costs and volumetric productivity at scale (Zhu et al., 2024)

doi: 10.1111/1462-2920.13589 68 WeingardenARChenCBobrAYaoDLuYWNelsonVMet al

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Oncogene 36 , 182193 (2017)

K.DaoudS.PetrovaP.RabayaO.JbaraA.Al HouqaniS.et al

Sometimes, these are significant changes, like during pregnancy or after a weight loss surgery