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In conclusion, these results indicate a protective role of GSTP1 by increasing enzymatic detoxification of AQ-QI and DEAQ-QI and suggest a second protective mechanism by interfering with ER stress induced apoptosis

It belongs to the -glutamylcyclotransferase family, and exclusively degrades reduced glutathione (and not oxidized glutathione) breaking it down into 5-oxoproline and cys-gly (1)

CXCR2-modified CAR-T cells have enhanced trafficking ability that improves treatment of hepatocellular carcinoma

Photoaffinity labeling of Arabidopsis thaliana plasma membrane vesicles by 5-azido-[7-3H]indole-3-acetic acid: identification of a glutathione S-transferase

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Therefore, it is suggested to researchers and clinicians that seeking the means to prevent or treat CIPN may become the key to effectively controlling cancer and improving the quality of life of cancer survivors