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Purpose Because vaccines are often given to healthy persons, benefit-risk assessments are conducted to ensure that the benefits of vaccines, such as preventing infection, outweigh possible side-effect risks, such as vaccine-attributable myocarditis/pericarditis (inflammation of the heart or of the membrane surrounding the heart, respectively)

ROS induces the activation of NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammatory bodies (Minutoli et al., 2016)

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Whether GHK-Cu is causing those changes or just correlating with them is part of the story we'll get into

doi: 10.1111/jop.12044 42 ConklinMWEickhoffJCRichingKMPehlkeCAEliceiriKWProvenzanoPPet al

Conclusion The overall limited number of cases worldwide, and the few toxicity studies available together with the preliminary determinations of regulatory organs seems to exclude the possibility of an intrinsic toxicity of curcumin