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Description

Best taken on an empty stomach

For cardiovascular goals specifically, community wisdom suggests starting at the lower end of the dosage range

This is also the structure Novo Nordisk's own investigational semaglutide+cagrilintide combination used in REDEFINE 1 (Garvey et al., NEJM 2025) both components stepped in parallel through a 16-week ramp rather than introduced together at maintenance