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Functional mapping of androgen receptor enhancer activity

A., Krantz, M

Intrinsic clearance is reduced by 39%

DT-13 synergistically enhanced vinorelbine-mediated mitotic arrest through inhibition of FOXM1-BICD2 axis in non-small-cell lung cancer cells

Although this view was later attenuated based on the head-to-head conformation of the DNA-bound DBD dimer that was observed in X-ray crystallography studies and observations of relaxed response element stringency for selective chromatin binding [51, 52], it did point to the potential of variability in the composition of AREs and to deviations from the ideal 15 bp sequence