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Extracell Vesicles 252 YeX.KuZ.LiuQ.WangX.ShiJ.ZhangY.et al

Clinical trials comparing alternative potentially beneficial therapies, alone or in combination, should be conducted in this important population.

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We noted that the prototypical conformational mutant R175H, which has previously been characterized as responsive to APR-246 [10], was neither significantly enriched nor depleted in the treated population (Supplementary Fig