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The supernatant S1 was also subjected to ultracentrifugation at 160,000 g for 60 min

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Impaired swimming speed in adult transgenic fish with LMNA mutations To investigate the effect of LMNA variants on the locomotion of adult transgenic fish, we conducted T-maze experiments to measure swim speed

Moreover, proteomics screening revealed that monocarboxylate transporter 1 (MCT1, protein for the SLC16A1 gene) and lactate dehydrogenase B (LDHB), responsible for lactate uptake and oxidation, respectively, were among the top three significantly upregulated proteins in AR cells (Fig