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The health risk assessment has been calculated by using the formula given below

Black SM, Wolf CR (1991) The role of glutathione-dependent enzymes in drug resistance

amyloid beta: the major component of amyloid plaques in Alzheimer's disease

At present, several chemically diverse families have emerged as GSK-3 inhibitors 16 , including peptides 17 , metal ions 18 , and diverse small heterocycles 19 , and the development of GSK-3 inhibitor recently became a potential therapy for AD

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Traditionally, laxatives have been the primary pharmacological approach for chronic constipation due to their availability, affordability, and tolerance by most patients