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The endocannabinoid system comprises (i) the endocannabinoids [natural cannabinoid substances in the body including 2-AG and arachidonoyl ethanolamide (anandamide)], (ii) enzymes involved in endocannabinoid synthesis and catabolism that regulate their concentration in the brain, and (iii) the cannabinoid receptor types 1 and 2 (CB 1 and CB 2 ) which transmit their signals in tissues and organs (Figure 2) [8]

These findings indicate that LicoA suppresses ferroptosis in HK-2 cells in an Nrf2-dependent manner

RalGDS is the key component that connects the KRAS pathway to other pathways

Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1 pathway

A bispecific antibody (ScBsAbAgn-2/TSPO) target for Ang-2 and TSPO resulted in therapeutic effects against glioblastomas

Clin Epigenet 15 , 132 (2023)