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Kichula EA, Proud CM, Farrar MA, Kwon JM, Saito K, Desguerre I, McMillan HJ (2021) Expert recommendations and clinical considerations in the use of onasemnogene abeparvovec gene therapy for spinal muscular atrophy

Additionally, they have antioxidant effects due to their scavenging activity for reactive oxygen or nitrogen species and by a reduction in oxidative stress (138, 141)

Sansome, D

Because of the enhanced bioavailability and decreased clearance of the nanoparticles, it is thought that a larger aspect ratio of the particles corresponds with increased cytotoxicity