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Therefore, the newly synthesized NRF2 accumulates in the cell, enabling it to exert its antioxidant and cellular protective functions [26]

The thiol is the working surface of glutathione, the reactive position on every cysteine residue, and one of the most versatile chemical handles the cell maintains

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Finally, K33-linked typical ubiquitination controls intracellular trafficking and autophagy (Heath et al

Dig Dis Sci

ROS have been shown to play a causal role in various cellular events, including proliferation, differentiation, metabolic adaptation, and the regulation of adaptive and innate immunity