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SIRT3-dependent GOT2 acetylation status affects the malateaspartate NADH shuttle activity and pancreatic tumor growth

This was accompanied by a reduced distribution of these proteins at the plasma membrane and an increase in IEC permeability

Enzyme samples were incubated with phosphate buffer, which included the appropriate concentrations of glutathione (GSH) and peroxide as substrates, to determine Gpx activity

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10.1523/JNEUROSCI.4453-08.2008 82 HartyB