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Scavenger receptor class B Type I deficiency induces iron overload and ferroptosis in renal tubular epithelial cells via hypoxia-inducible factor-1alpha/transferrin receptor 1 signaling pathway

The GST family consists of three superfamilies: the cytosolic, mitochondrial, and microsomalalso known as MAPEGproteins

The standard procedure and reagents from the Q5 Site-Directed Mutagenesis kit (NEB) were used to insert mutations, ligate plasmids and transform them into NEB 5 competent cells by heat shock

Additionally, transcription factors p53 and NRF2 also play significant roles in ferroptosis

Mold toxicity is very common and it is estimated that approximately 25% of the population does suffer from mold toxicity-the inability to process mold mycotoxins which leads to a series of biochemical alterations often called the Cell Danger Response

HDAC inhibitors can suppress the expression of MMP14 in GBM, and the inhibition of MMP14 helps to reduce tumor angiogenesis, inflammation, cancer cell invasion, and metastasis, thereby promoting tumor radiotherapy resistance