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Description

Nature.2000;403:77681

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GonalvesRFVicenteAAPinheiroAC

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Clinical data show that ACSL1 exhibits a positive correlation with FSP1, while it shows a negative correlation with 4-hydroxynonenal (4-HNE) and prostaglandin-endoperoxide synthase 2 (PTGS2)

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The end of the loop contains a valine within a highly conserved TVP signature in class I GRXs

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No other medication was given during the study

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Together, they drive syn misfolding, aggregation, and neuronal degeneration

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