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The cancer-associated vasculature is characterized by an increased permeability and interstitial fluid pressure due to the disruption of ECs junctions, which reveals to be pivotal in cancer cell adhesion, intravasion and metastasis ( Figures 3A, B ), which results in the generation of a leakier ECs structure

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Proc Natl Acad Sci USA 2014

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Facial twitching There is evidence that low levels can also cause facial twitching, which is likely to occur as the nerves in the face become progressively damaged

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