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Exposing cerebral mitochondria to THC was reported to induce a ten-fold increase in free radical leak and increased H 2 O 2 production [40], while in epithelial cells, THC upregulated inflammation-related genes and downregulated antioxidant-related genes [34]

Journal of Medicinal Chemistry, 61(4), 1382-1414

PMID: 94 LiuTHanSYaoYZhangG

Quantification of metabolites by LC-MS/MS To quantify polar metabolites concentrations, we used TSQ Vantage LC-MS interfaced with Ultimate 3000 Liquid Chromatography system (Thermo Scientific) and Triple quadruple mass spectrometry to detect metabolites from tissues or cells

Prospeo handles LinkedIn compliance updates, but if LinkedIn changes its ToS or anti-scraping measures, you may need to pause extraction temporarily

Moreover, it promotes mitochondrial damage via reactive oxygen species (ROS) accumulation [30] and synergizes with doxorubicin (DOX) to exert potent antitumor effects [31]