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Thiol-disulfide signalling ofreducedTRX TRX Figure 8

Application No: 60/907,176

Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease

- If a portion of a single use vial is discarded, the JW modifier may be used on a separate line of the claim to report the discarded amount

Given that all three subunits of RPA are expressed at high levels in vegetative yeast, it still seems likely that the interaction between Mer3 and RPA is mediated primarily through Rfa1