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It alleviates motor fluctuations without increasing troublesome dyskinesia

[DOI] [PubMed] [Google Scholar] 307.Zhang T, Deng R, Wang Y, Wu C, Zhang K, Wang C, Gong N, Ledesma-Amaro R, Teng X, Yang C, Xue T, Zhang Y, Hu Y, He Q, Li W and Li J, Nat

5,61 As an example, orally administered GSH ethyl ester is able to significantly raise GSH concentrations in the liver, kidney, spleen, pancreas, heart, and lung of the mouse, and in human red blood cells, skin fibroblasts, and several lymphoid cell lines

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The distribution of these isomers can influence physicochemical properties such as solubility, stability, and antioxidant activity, and may therefore affect bioavailability and biological function