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The STEP trials, which led to FDA approval of Wegovy, all used subcutaneous injection

Gynecol Oncol 127:241248

Potential Benefits Strong support for fat loss Helps maintain or build lean muscle Enhances recovery and energy Improves sleep quality May help reduce inflammation markers Who It May Help Adults wanting fat loss + muscle maintenance Men and women looking for a metabolic reset Individuals transitioning off GLP-1 medications Active adults wanting better body composition Possible Side Effects Temporary bloating or mild water retention Mild joint stiffness Vivid dreams Increased appetite (Tesamorelin can raise ghrelin slightly) When to Expect Results Improved energy, sleep, and recovery: 34 weeks Abdominal fat reduction: 812 weeks Administration Patients will self-inject this medication at home

Statements Author contributions Conception and design of study: QY, LK

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Thonningianin A, a newly identified ferroptosis inhibitor, activates GPX4 through the AMPK/NRF2 pathway (113)