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The pooled effect size was homogenous ( I 2 = 0%) (Fig

The results confirmed that Tbx1 +/ and Df1 / + brains have increased concentrations of MMA compared with WT controls (all animals were PBS-treated), and they showed that although vB12 treatment had no impact on MMA in WT animals, it was restored to WT levels in both of these mutants (Fig 3)