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Dysfunctional AT leads to low adiponectin and high leptin levels, causing hepatic insulin resistance and increased lipolysis, further accelarating the development and progression of NAFLD

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There are several factors, in addition to drugs described earlier, such as age, sex, diet, diabetes mellitus (DM) type 2, or chronic kidney disease that can affect plasma apoC-II concentration

Antiviral therapies, mainly based on the combination of IFN and ribavirin can only assure a long term eradication of the virus in less than half of treated patients

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