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a master regulator of genes involved in the uptake of iron and iron-containing moieties in many bacterial species (Hassan and Troxell, 2013)

These numbers deserve careful consideration

Furthermore, TNF- enhances the expression of adhesion molecules on sinusoidal endothelial cells, particularly intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule 1(VCAM-1), promoting firm adhesion and aggregation of neutrophils and aggravating microvascular obstruction and tissue damage (54)

PMID: 30984863

This coenzyme acts as a delivery mechanism for electrons moving to and from enzymes in mitochondria, the energy-producing centers of cells

Of these loci, 41 are specific to CD, 30 are specific to UC, and 137 are shared between both diseases [19,20,21,22]