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Alzheimers Res Ther 5: 48 Mufson EJ, Ma SY, Cochran EJ, Bennett DA, Beckett LA, Jaffar S, Saragovi HU, Kordower JH (2000) Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

doi:10.3389/fendo.2021.645563

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10.1016/j.ejphar.2025.177468 202 WangJ.ZhangF.TanC.WangN.XiaX.YeY.et al (2025b)

Using RUO peptides in humans carries unacceptable risk because these materials havent undergone FDA review for safety, efficacy, dosing, sterility for injection, or consistent manufacturing quality