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MAGEL2 was shown to modulate the stability and activity of key circadian regulators including CLOCK, BMAL1, and PER2 ( The biological importance of MAGEL2-mediated regulation of clock proteins is underscored by the circadian phenotypes observed in MAGEL2 knock-out mice

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In a letter, the FDA confirmed that nominations for several peptides had been withdrawn and that these substances would be removed from Category 2 from April 22

By elucidating the physiological mechanisms underlying normal neurological function and the pathogenesis of diseases, this review provides a novel perspective on understanding synaptic regulation and dysfunction

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