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Low-dose rapamycin, by inhibiting mTOR activity, reduces the expression of pro-inflammatory proteins and stifles mTOR-driven aging (Mizumura and Gon 2021)

The -oxidation pathway consisting of 2-E-valproic acid, 3-OH-valproic acid, and 3-keto valproic acid was decreased from 25% of total metabolites excreted on valproate alone to 8.3% in the presence of aspirin

Ganoderma lucidum polysaccharide ameliorated diabetes mellitus-induced erectile dysfunction in rats by regulating fibrosis and the NOS/ERK/JNK pathway

10.1038/s41598-022-05470-x 4 AltmanB

Thereafter, 7 positive and 7 negative metabolites, alongside 6 proteins that had shown significant changes in COPD patients (P max = 0.029) were individually subjected to ROC analysis, to evaluate their sensitivity and specificity and help discriminate COPD from healthy controls

doi:10.1007/s10637-010-9386-6 Lhr JM, Karimi M, Omazic B, et al