formaldehyde reactivity glutathione Emerging mechanisms underlying toxicity and response: Molecular Cell Site of Reactivity Models Predict
Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione S. Joshua Swamidass, MD PhD Amino acid dependent formaldehyde metabolism in mammals Communications Chemistry Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity Nature Communications Integrative Modeling of Oxidative Stress and C1 Metabolism Reveals Upregulation of Formaldehyde and Downregulation of Glutathione Illuminating cellular formaldehyde Nature Communications The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL 6 mice Genes and Environment Springer Nature Link
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