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Agricultural and environmental chemicals can also induce AKI, with the toxicological pathways of many pesticides related to oxidative stress, potentially through their metabolites, mitochondrial damage, or inhibition of cellular antioxidant defense systems (87)

The compound did not appear to affect food intake, behavior, or general health status in treated animals

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In vitro experiments indicated that incubation with CGA at its IC50 concentration for 96 h resulted in the arrest of L-02 cells in the S phase of the cell cycle and induced apoptosis

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