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S7A-C).To determine whether blocking TDP-43 SUMOylation leads to phenotypes in an age-dependent manner, we assessed general wellness biweekly, including measuring body weight and hindlimb clasping scores, and performed a battery of 14 behavioral tests focusing on motor, social, and cognitive function related to ALS and FTD at three time points (2, 9 and 16 months, Fig

There are different types of nanoparticles, including polymeric nanoparticles, lipid-based nanoparticles, inorganic nanoparticles, and biological nanoparticles

ER expression is widespread throughout the body

The technology utilizes microbubbles that expand and contract when activated by low-intensity ultrasound energy

J Neuroimmune Pharmacol (2020) 15(1):7481