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Osteoclast differentiation factor Denosumab (DMab) is a human monoclonal IgG2 antibody that inhibits bone resorption by binding and inhibiting the receptor activator of the NF-kB ligand (RANKL), an essential cytokine for osteoclastogenesis and bone resorption

doi: 10.1111/j.1572-0241.2007.01260.x 97 HernandezL.WardL

Furthermore, it has been reported that the use of ursodeoxycholic acid seems to have a positive influence on the prevention of radiation-induced liver disease after radioembolization in patients with liver metastases from breast cancer (202)