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By increasing the expression of SIRT1, resveratrol can alleviate renal fibrosis and muscle atrophy in 5/6-nephrectomized (5/6Nx) rats

doi: 10.3390/ijms24021526 205 SaitouM.FuruseM.SasakiH.SchulzkeJ

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors

In the case of immune cells, this results in attenuated surveillance and immune evasion, whereas in stromal cells it may lead to maladaptive metabolic reprogramming [370, 451]