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Using the targeting of nanoparticles, the encapsulated engineered bacteria can specifically aggregate at the tumor site of HCC [145]

In KRAS mutant models, macrophages promote copper uptake via a non-classical pathway to supply bioavailable copper for tumor growth, while ATP7A alleviates copper toxicity through efflux mechanisms

DES drives anabolic processes and increases protein synthesis, requiring caloric surplus and adequate protein for optimal effect

10.3390/ph16091318 120 WangJ.WuD.GuoH.LiM

How about that for a vicious cycle