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Nanocarriers for delivering STING agonists include liposomes [20, 187], cationic polymers [188], inorganic nanoparticles [43, 98, 189, 190], polymeric micelles [191], vesicles [192], exosomes [193], and bionanoparticles [109]

GSH depletion can be a consequence of the inactivation of SLC7A11 of system Xc- which impairs the importing of cystine and hence the available cysteine needed for GSH synthesis [15]

ab195964, Abcam) overnight at 4 C, followed by incubation with Alexa Fluor 555-, 647- or 405-conjugated antibodies, respectively, at room temperature for 1 h

Dexmedetomidine ameliorates myocardial ischemia-reperfusion injury by inhibiting MDH2 lactylation via regulating metabolic reprogramming