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ENT1 and ENT2 are found in most cell types and tissues, and ENT4 is located in the brain and heart

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The pathophysiology of PD is characterized by -synuclein accumulation and the degeneration of dopaminergic neurons in the substantia nigra 2,3

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Mateuszuk , Khomich TI, Somiska E, Gajda M, Wjcik L, omnicka M, Gwd P, Chopicki S (2009) Activation of nicotinamide N -methyltrasferase and increased formation of 1-methylnicotinamide (MNA) in atherosclerosis