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The genetic variant of GSR (rs8190955) was also found to be significantly associated with anaemia

Other HIF-1 activities include the transcriptional regulation of metabolic enzymes such as lactate dehydrogenase A and pyruvate dehydrogenase kinase 1, which control the flow of carbon substrates into the mitochondria [37,38]

PMID: 60 MathurJ.PanwarR

& Barrows, J

Baseline matters

Additionally, for follow-up studies, it would be interesting to include a control with heat-inactivated HIV in the MNO condition, to be able to better differentiate between replication-dependent and independent effects of the virus in the presence of microglia