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Bioreactor temperature during infection was investigated to maximize titer, and a decrease in temperature from 37C to 34C yielded a twothree-fold increase in infectivity

The shedding typically lasts 2 to 4 weeks and signals positive response

LPC and cuprizone demyelination induce transcriptionally similar DAM states that persist through remyelination In addition to OL lineage alterations, demyelination induced dramatic changes in microglia abundance and state (Fig

The interplay between HAS3-mediated HA synthesis and HYAL1-driven degradation further exemplifies intrinsic temporal control of ECM remodeling, providing a natural biological model that parallels HAGSH scaffold responsiveness [19]

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doi: 10.1093/schbul/sbt114, 115