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It is worth noting that flavonoids encompass many compounds beyond those detailed here

The aforementioned factors may influence the breakdown of immunotolerance, leading to an autoimmune attack on the thyroid (32)

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years

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Therefore, decreasing the dose is probably inadvisable