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[6] [42] [43] For single doses of lipophilic, multi-compartment drugs, clinical duration after onset is often driven by the distribution () phase, because by the time distribution equilibrium is reached plasma levels are frequently below any minimal effective concentration, so the terminal phase has little bearing on observable effects

Because biopsies generate both professional and pathology claims, payer systems often cross-check procedural notes against pathology billing patterns to ensure clinical and documentation consistency

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Stinson FS, Grant BF, Dufour MC